Feb 16, 2007 · Receptor tyrosine kinases (RTKs) are essential components of signal transduction pathways that mediate cell-to-cell communication.
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RTKs utilize several signaling pathways, including MAPK/ERK, PI3K/Akt/mTOR, and PLCG1/PKC. These pathways regulate the transcription of numerous genes whose ...
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Signal binding to membrane receptor tyrosine kinases (RTKs) activates an enzyme called a kinase. Learn how kinases initiate a signaling cascade that relays ...
Receptor tyrosine kinase
Protein
Receptor tyrosine kinases are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90 unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase... Wikipedia
Gene Ontology: AmiGO / QuickGO
PDB structures: RCSB PDB PDBe PDBsum
Aug 31, 2023 · Receptor tyrosine kinases mediate responses to a large number of signals, including peptide hormones like insulin and growth factors like ...